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Dosage:10 mg/kg (Female STZ-diabetic), 30 mg/kg ( db/db mice, male control) Administration:p.o., daily, 16 weeks (Female STZ-diabetic), 26 weeks ( db/db mice, male control) Result:Significantly protected long-term memory and attenuated reductions in the volume of the CA1 and DG regions in type 1 diabetic mice

Bioorg Med Chem 2014;22:6193200

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