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The effects of hormonal ADT in suppressing tumor growth and delaying metastasis was first reported in 1941 and is thought to be related to the ubiquitous expression of androgen receptors in prostate cancer and the dependence of tumor cell growth on the transcription of specific pro-survival genes downstream from androgen receptor signaling (Harris et al., 2009)
2011, 6: 19- Michel SJ, Given CA, Robertson WC: Imaging of the brain, including diffusion-weighted imaging in methylmalonic acidemia
American Journal of Nephrology, 3(4), 205208
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