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BBB dysfunction leads to increased permeability, allowing inflammatory mediators and immune cells to infiltrate the brain, which contributes to neuroinflammation and the development of depressive symptoms [189]

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The addition of degradable chelating agents enhances maize phytoremediation efficiency in cd-contaminated soils

doi: 10.3390/ijms22073789 90 AboeldalylSJamesCSeyamEIbrahimEMShawkiHE-DAmerS

Taken together, this report highlights the power of integrating total synthesis with late-stage modifications, guided by a structure-based design, to engineer novel abiotic TF with refined activity