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Recently a meta-analysis examined the possible link between mitochondria and autism, the conclusions of this study are that it is not clear if mitochondrial dysfunction contributes to the development or pathogenesis of ASD or if mitochondrial dysfunction is just an epiphenomenon of ASD[14]

A L-carnitina um aminocido naturalmente presente no organismo, essencial para o transporte de cidos gordos para as mitocndrias, onde so convertidos em energia

Meyer-Ficca ML, Ihara M, Bader JJ, Leu NA, Beneke S, Meyer RG Spermatid head elongation with normal nuclear shaping requires ADP-ribosyltransferase PARP11 (ARTD11) in Mice1

Disorders Associated with Carnitine Metabolism Diseases related to carnitine metabolism include primary carnitine deficiency (PCD), secondary carnitine deficiency (such as diabetes, kidney disease, etc.), and congenital defects (such as CPT II deficiency, CACT deficiency, etc.)

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The observed reduction in CARS scores following the GF-MKD intervention is consistent with previous studies reporting behavioral improvements in children with ASD following ketogenic or high-fat, gluten-restricted dietary interventions [35, 36]