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Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs

doi: 10.1073/pnas.0908869107

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For example, when silver was first used in dentistry, patients underwent procedures without anesthesia and many surgeries were fatal

The molecular interaction analysis further highlighted the significance of Tyr-326 in aromatic interactions, along with the presence of a critical hydrogen bond with Cys-172, essential for anchoring MAO-B inhibitors

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