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Acknowledgements The authors express their thanks to the Mayo Clinic Metabolomics Core for their support and assistance during the study

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Diagnosis of Vitamin B12 deficiency involves a blood test to measure serum B12 levels, along with other relevant diagnostic tests like complete blood count (CBC) and peripheral blood smear

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It contains no preservative and matches physiological ionic strength useful for isotonic compatibility studies but not the general reconstitution default

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Inclusion of the CDs increased the EE up to 81%

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PLoS One 12, e0181863

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For example, the Wnt signalling pathway is related to the development and renewal of small-intestinal epithelial tissue and promotes the differentiation of Paneth cells at the base of the crypt

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