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We circumvented the need for CYP-mediated bioactivation of AQ and DEAQ by exposing the cells to the synthetic AQ-QI and DEAQ-QI, the reactive metabolites of AQ

Molecules 24, 492495

In addition to its epigenetic and anticachectic properties, resveratrol exerts direct antitumor effects in CRC through multiple mechanisms

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However, xCT has been demonstrated to play contradictory roles in ferroptosis regulation in a tumor-promoting or suppressive manner, depending on changes in energy and nutrient metabolic pathways [48,57]

Unfortunately, Th2 response alone does not adequately control the intracellular pathogens and antibodies seen in HIV, and patients are unable to neutralize the virus