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In ART-treated PWH, CMV infection is nearly universal, amplifying HIV-induced immune activation and contributing to non-AIDS-related comorbidities [128]

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These enzymes constitute the primary cellular defense against reactive oxygen species (ROS), and their expression declines with age in many tissue types

Another non-selenium glutathione peroxidase, GPx7, which lacks GPx activity, has recently been described as a novel phospholipid hydroperoxide GPx [11, 19,20,21]