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Gels in general exhibited smaller AUC, lower C max, and shorter T max when compared to their corresponding MN formulations indicating the effect of MN in bypassing the corneal barrier and delivering the drug directly into the deeper ocular tissues

Emerging strategies are reported to include modulation of synaptic plasticity and neurotransmission, delivery of neurotrophic factors, activation of intrinsic cytoprotective pathways (e.g., Nrf2 signaling), restoration of proteostasis, and induction of regeneration via cellular reprogramming

To inform policymakers, strengthen research coordination, support early-career scientists, and ultimately improve outcomes for millions living with hormone-related diseases