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Description
Storage: sealed amber-glass vial under inert gas
The causes can be broadly categorised into exogenous (external) and endogenous (internal) factors, with the latter being of greater clinical significance
What are your areas of concern
In the STEP and SURMOUNT trials: Constipation was reported in up to 24% of patients on semaglutide 18-23% of patients on tirzepatide experienced constipation It is one of the top three side effects of these medications and is more frequent in those who: Lose weight rapidly Eat low-fiber diets Are female (due to hormonal factors affecting gut motility) Conventional Treatment Approaches Most providers recommend over-the-counter (OTC) remedies such as: Stool softeners (docusate) Fiber supplements (psyllium, methylcellulose) Laxatives (PEG 3350, senna, Mag Citrate) These can help in the short term but do not address the root cause
Choosing the wrong one does not just fail to help: it can worsen inflammation, trigger hyperpigmentation, or damage a compromised barrier
Sorrell, Thomas, N
