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In contrast to the orthosteric site, which is well-defined with respect to its location and ligand binding, allosteric sites across the receptor surface vary greatly
Yellowing of the skin If you notice that your skin is starting to look yellow, it could be a sign of a vitamin B12 deficiency
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doi: 10.1517/17425255.2011.577738
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Khavinson VKh, Pendina AA, Efimova OA, Tikhonov AV, Koltsova AS, Krapivin MI, et al
