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Dissecting the role of the mitochondrial chaperone mortalin in Parkinsons disease: functional impact of disease-related variants on mitochondrial homeostasis

[19] [21] Dosage adjustments may be necessary in patients with renal impairment, G6PD deficiency, or other comorbidities

On the other hand, based on our structural observations and our kinetic assays, the highly conserved residue Gln64 would seem to be essential for the binding of GSH and for catalysis (Fig

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Food and Drug Administration (FDA) accepted Eisais Biologics License Application (BLA) for the LEQEMBI subcutaneous autoinjector for weekly maintenance dosing in January 2025 and set a PDUFA action date for August 31, 2025

Mitochondrial criticality: a new concept at the turning point of life or death