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This includes bones (ilium, femur, and tibia), tendons (all four parts of the quadriceps muscle ultimately inserted into the tuberosity of the tibia via the patella, where the quadriceps tendon becomes the patellar ligament), joints, neurovascular elements, and the muscles responsible for moving the legs [23]

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Thus, DN30 with dual effects on c-Met and HGF separately can inhibit the c-Met/HGF pathway [173]

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Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia