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Therapeutic efficacy and mechanistic insights of ADSCs in ED: in vivo and in vitro perspectives Animal models, particularly rodents such as rats and mice, are indispensable for elucidating the pathophysiology of ED and for preclinical evaluation of novel therapies (e.g., cavernous nerve crush, diabetic or hyperlipidemic models)

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An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII