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For quantitative determination, it is recommended to determine the serum zinc content as a screening test parameter

Trivedi A

These results demonstrate that excessive copper triggers FDX1-dependent aggregation of lipoylated TCA cycle proteins and destabilization of Fe-S cluster proteins, consequently leading to cuproptosis

Research indicated that these bioactive compounds have potent antioxidant and antiinflammatory properties, have garnered significant attention for their potential role in combating AD by targeting its key pathological mechanisms
Among these, high-penetrance monogenic forms of PD mainly include SNCA, VPS35, PRKN/PARK7/PINK1, while genes with variable penetrance primarily include LRRK2 and GBA [16]

BMB Rep 52:349359 [DOI] [PMC free article] [PubMed] [Google Scholar] 76.Kim J, Daadi EW, Oh T, Daadi ES, Daadi MM (2022) Human induced pluripotent stem cell phenotyping and preclinical modeling of familial parkinsons disease
