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Description
This mechanism is particularly relevant against Gram-positive bacteria, which have a thick peptidoglycan layer that is more susceptible to membrane-targeting agents [154]

[DOI] [PMC free article] [PubMed] [Google Scholar] 759.Eckardt K., Grgens S.W., Raschke S., Eckel J

Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: A drug discovery effort against alzheimer's disease
Xing Dai's lab in the Department of Biological Chemistry

This should involve establishing stable preclinical models to first conduct in vitro experiments for screening combination regimens with potential synergistic effects and low interaction risks

Interactions of zinc-and redox-signaling pathways
