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The lifespan of neutrophils and monocytes (the host cells) in the blood is short and can last a few hours (in the case of neutrophils) to a few days (for monocytes)

doi: 10.3389/fphar.2025.1656862 Received 30 June 2025 Accepted 26 August 2025 Published 08 September 2025 Volume 16 - 2025 Edited by Perisamy Saravanan, Rajalakshmi Engineering College, India Reviewed by Xinyu Wang, Philadelphia College of Osteopathic Medicine (PCOM), United States Patricia Quintero Rincn, University of Antioquia, Colombia Updates Copyright 2025 Meng, Cui, Li, Shang and Chen

Among the key genes implicated in this process are tyrosinase (TYR), tyrosinaserelated protein 1 (TYRP1), tyrosinaserelated protein 2 (TYRP2), microphthalmiaassociated transcription factor (MITF), paired box gene 3 (Pax3), SRYbox transcription factor 10 (Sox10), melanocortin 1 receptor (MC1R), tyrosine kinase receptor (cKit), Plexin C1 (Plexin C1), MelanA (MelanA), premelanosome protein (Pmel17), and the receptor for hepatocyte growth factor (MET)

Effect of different formulations of propolis on mice infected with Trypanosoma cruzi

Suppressed oxidative distress in those cases may have a negative impact on health