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Increased intra-abdominal pressure also increases intrathoracic pressure, which is rapidly transmitted up through the venous system, thereby further increasing intracranial pressure (Malbrain and Wilmer, 2007

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[DOI] [PMC free article] [PubMed] [Google Scholar] 210.Wang S.K., Weaver J.D., Zhang S., Lei X.G

However, the removal capacity declines with age (partially due to the immunosenescence), resulting in the increased SASP

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doi: 10.1371/journal.pone.0202919
