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Reaction time as well as the ability to switch between tasks was improved by combination therapy at lower doses, i.e., 50 mg caffeine plus 100 mg l-theanine [81]

doi: 10.1016/j.bbi.2008.06.005

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Overall, the researchers found that the APP/PS1 mice treated with Dihexa exhibited a significantly better performance in comparison to the control mice when assessing the number of platform crossings

Calcium influx was measured using flow cytometry for 5 min on a BD FACSymphony A5 flow cytometer, and calcium flux was quantified as the ratio of Indo-1 emission at 400 nm (bound Ca 2+ ) to 475 nm (free Ca 2+ )