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Dermatologists stress that without adequate sun protection, new pigmentation can emerge, counteracting the benefits of glutathione

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In these systems, nicotinamide adenine dinucleotide phosphate (NADPH) acts as a source of reducing equivalents through two flavoenzymes oxidoreductases: glutathione (GSH) reductase (GR, EC 1.8.1.7) and thioredoxin (Trx) reductase (TR, EC 1.8.1.9) 23