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OCTN1 is also expressed in brain parenchymal cells, including neurons, and ERGO in the blood permeates the bloodbrain barrier and is distributed to the brain, exhibiting a neuroprotective effect

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However, the pathological importance of neutrophil oxidants is still not clear

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As a result, indoxyl sulfate, phenyl sulfate, and p-cresyl sulfate decreased glutathione levels in porcine renal tubular cells