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One prime example is the discovery of the nutrient sensing mechanism for cholesterol, which led to the development of life-saving statin drugs (and the Nobel Prize)
doi: 10.1016/j.cca.2006.08.024
TB-500: Which Peptide for Lyme
Although zebrafish liver disease models are widely employed, a dedicated methodological synthesis evaluating their application specifically for phytochemical researchfrom model establishment to mechanistic validationis lacking
DOI: 10.1046/j.1365-313X.2003.01730.x 107
