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This effect was also noted in somatosensory orientation of sulpiride (20, 40, 80, and 160 mg/kg b.w., i.p.) treated animals, although no catalepsy could be observed in control sulpiride mice

ACS Synth Biol 2022, 11 (10), 33793387

[DOI] [PubMed] [Google Scholar] 97.Monaghan G, Ryan M, Seddon R, Hume R, Burchell B

29 A high-fructose diet can also trigger symptoms of metabolic syndrome and increase oxidative stress and inflammation, reducing glutathione

These two steps resemble the first two reactions in the Krebs cycle, catalyzed by citrate synthase and aconitase, respectively