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CREB also controls the transcriptional activation of various signaling molecules, including c-Fos, c-Jun, and BDNF, thereby facilitating neuronal cell survival, differentiation, migration, and synaptic generation (368, 369)
10.1371/journal.pone.0034772 PLoS One
Similarly, another recent 1H MRS study reported lower in vivo levels of GSH in the COC of unmedicated adults with MDD versus healthy controls (39)
This test does not require trained personnel unlike flow-mediated vasodilation (FMD) which requires sophisticated instrument, a skilled operator and has a chance for large inter-individual variability in the assessment of ED [17, 24]
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