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Chronic inflammation, characterised by elevated levels of hepcidin and diminished iron absorption, also contributes to iron deficiency [19]

[DOI] [PMC free article] [PubMed] [Google Scholar] Serhan C

Although one of these sites is located in the 5 promoter region and the other site in the 3 flanking region, both sites are functional, as they have both been shown to bind the PU.1 nuclear factor in gel mobility shift assays, and both mediate transcription, as assessed by reporter gene assays

Apoptosis is induced by two main routes involving either the mitochondria (the intrinsic pathway) or the activation of death receptors (the extrinsic pathway) (Fig

female = 20), P20 (male = 14