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The outer surface of CTL1 is mostly neutral to positively charged, whereas distinct positive (Lys544, Lys454, Arg457, His584, and Lys491) and negative (Asp537, Glu591, and Asp595) patches are observed close to the entrance of the proposed binding pocket (Fig 4G)

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Wound-healing complications are particularly common in smokers or patients with certain medical conditions

One patient was lost sight of post-operative without further follow-up

1, along with detailed results of statistical analyses

These lesions, ranging from benign melanotic macules and physiological pigmentation to melanomas and indicators of systemic diseases, pose formidable diagnostic challenges