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In the synthesis method of cagrilinteide, the Vc reagent is prepared by dissolving Vc per gram in 20-30mL of purified water
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Notably, 31c does not affect the antitumor effects of cisplatin in cancer cells while effectively protecting HK-2 cells from cisplatin-induced toxicity (Wei H
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Yet, many patients exhibit limited or resistant responses, underscoring the need for more effective and rational immunotherapeutic approaches (51, 114116)
