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This work was supported by the Department of Defense Peer Reviewed Medical Research Program grant PR141776 (S.J.W.), University of Texas Medical Branch Technology Commercialization Award (S.J.W), and NIH grant R01GM112936 (C.C.F)

Theoretical concerns include excessive NAD+ elevation in individuals with preexisting metabolic disorders or mitochondrial dysfunction

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Chronic treatment with AOD 9604 in obese mice produced significant weight reduction and changes in fat pad weight

(a) pipeline employed in our project
