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Degraded in GI tract Hepatic first-pass processing Absorption varies by formulation Glutathione Injection Bypasses gastrointestinal processing entirely

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Science 375 , 12541261 (2022)

What Do We Need Glutathione For

The infants received supplementation of NAC doses ranging from 70 to 150 mg/kg/day and L-cysteine doses ranging from 85 to 300 mg/kg/day [97]

If the ratio shifts too far toward the oxidized state, it means the body is struggling to keep up with the demand for antioxidants