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10.1186/s13046-018-0843-y 171 MooreL

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This vulnerability occurs because the cells cannot maintain enough active glutathione to neutralize harmful "free radicals" unstable molecules that can damage cellular structures

ALI mouse model was established by injecting overdose (350 mg/kg) of APAP
But in cancer cells, pyruvate dehydrogenase complex activity may be dampened 166,231

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