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Currently, hormetic nutrients and agents modulating vitagenes are also drawing increasing attention of inhibiting ferroptosis due to their protection against oxidative stress and neuroinflammation in CNS diseases

The AS may affect lymphocyte, monocyte and macrophage activity resulting in immune-suppression

Neurol Sci 39(11):18871894

Moreover, in light of findings demonstrating that neutrophils produce IL-6 upon incubation with respiratory syncytial virus (a single-stranded RNA virus) 12 , recognize HIV-1 vi a TLR8 13 and express a broad repertoire of functional PRR involved in the recognition of nucleic acids of viral origin 6,7 , our data have further corroborated the notion that neutrophils should be included among the cells responding to viral infections 14

Dysfunctional mitochondria produce more ROS, which can further impair mitochondrial function

Unraveling the truth about antioxidants: mitohormesis explains ROS-induced health benefits