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Mitophagy in alzheimers disease and other Age-Related neurodegenerative diseases

It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances (Green et al., 2017)

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Brain Behav 11:e2408 [DOI] [PMC free article] [PubMed] [Google Scholar] Perin MT et al (2023) Homocysteine levels, genetic background, and cognitive impairment in Parkinsons disease