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The physiological relevance of CETP inhibition by apoC1 was first confirmed in vivo in transgenic mice expressing human CETP (CETP-Tg) crossed either with apoC1-knocked out mice (apoC1-KO mice), or with mice overexpressing human apoC1 (apoC1-Tg mice)

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At this point, we were unable to determine whether this effect is direct or indirect

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the number of hydrogen atoms attached to the carbon skeleton is maximized semi-permeable membrane membrane that allows certain substances to pass through steroid type of lipid composed of four fused hydrocarbon rings forming a planar structure triacylglycerol ( also triglyceride ) fat molecule