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The dose was gradually increased resulting in significant improvement in parkinsonism and dystonia

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Briefly, the MiaPaCa2 tumor-bearing mice received either vehicle (HPCD) alone or 200 mg/kg CB-839 by oral gavage twice a day for 4 days, with or without a single sub-efficacious dose of -lap at 25 mg/kg IV on day 4

13 , 11461152 (2011) Schwartz, G