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Senescent fibroblasts and endothelial cells, through the secretion of SASPparticularly PDGF-Apromote an increase in myofibroblast numbers at wound sites, which positively affects wound healing [141]

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Cytokine regulation When youre injured, or after surgery, your body releases proteins called cytokines
Evidently, the principle rapidly functions as promptly reestablished and reorganized blood flow (i.e., activated collateral circulation) when the upgraded minor vessel can take over the function of the injured major vessel and overwhelm the Virchow triad circumstances, which is otherwise commonly presented (for review, see i.e., [1,2,3,4,5,6,7])
