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Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product

However, the early explorations of cuprizone toxicity used mice of varying strains, sex, and ages, which complicates interpretations of findings between experiments, thus highlighting the need for a more standardized approach

The effect of coenzyme Q 10 on blood pressure needs to be examined in large, well-designed clinical trials

& Santra, S

It should be noted that more than half of acetaldehyde in the brain is attributed to CAT [28], as well as that that acetaldehyde is a very toxic product and can further trigger the production of ROS, which includes both reactive molecules and free radicals derived from molecular oxygen [11,27]