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This validates the slower titration approach described in the protocol section above

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Immune cell crosstalk in type 1 diabetes

All weight loss interventions cause some lean mass loss alongside fat loss

14 Liraglutide and semaglutide, originally developed for people with Type 2 diabetes mellitus (T2DM), are approved for chronic weight management in people with obesity (or overweight and 1 weight-related comorbidities

7 Mitochondrial quality control and inflammation Mitochondrial quality control provides essential homeostatic functions including the regulation of the mitochondrial population to meet cellular energy demands, as well as the disposal of damaged mitochondria (Marchi et al., 2023)