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doi: 10.3389/fendo.2012.00131 107 YangSYGoldspinkG

Several mechanisms are thought to be responsible for the negative symptoms, such as, for example, the effect of the disease on glutaminergic synapses [66]

Overall, theyre quite safe

Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimers disease-like lesions

This elegant therapeutic approach sees its efficacy, however, crippled by several factors: (i) the number of nanoparticles that accumulate in the tumor is usually low due to a reduced targeting efficiency 5 , (ii) the properties of the tumor microenvironment limit the generation of ROS, and (iii) the optical properties of the tissues drastically reduce the amount of light that can reach the NPs housed intratumorally 6

10 Containment systems are now available for both power and manual morcellation