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In conclusion, despite the extensive information available on green tea and tea catechins to date, there remain numerous unknowns about the pharmacokinetics and pharmacodynamics of catechins

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Patients and providers should treat them as directional rather than definitive, and decisions about participating in trials or accessing investigational therapies should always involve a specialist in endocrinology or metabolic medicine

Hafez HM, Ibrahim MA, Ibrahim SA, Amin EF, Goma W, Abdelrahman AM (2015) Potential protective effect of etanercept and aminoguanidine in methotrexate-induced hepatotoxicity and nephrotoxicity in rats