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Quercetin is a free radical scavenger shown in studies to help prevent oxidized cholesterol.[ref] This is important because oxidized cholesterol may accelerate atherosclerosis or plaque build-up in the arteries.[ref] A double-blinded, placebo-controlled cross-over trial in overweight adults with metabolic syndrome found that 150mg/day of quercetin decreased the concentration of oxidized LDL cholesterol

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Clinical spectrum and features of activated phosphoinositide 3-kinase delta syndrome: A large patient cohort study

10.1186/s43556-023-00142-2 19 Fernandez-RebolloE.FranzenJ.GoetzkeR.HollmannJ.OstrowskaA.OliverioM.et al (2020)

(34457354) Seizures occur in ~20% of patients (including convulsive and nonconvulsive status epilepticus)