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Integrate nutraceuticals into a broader care plan that includes diet, exercise, and evidencebased integrative therapies (e.g., acupuncture for neuropathy)

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Selective binding of glutathione conjugates of fatty acid derivatives by plant glutathione transferases

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While polymorphisms in UGT , CYP , SULT and GST genes are well established [22,23,8992] and might affect the response to acetaminophen, only polymorphisms in UGT genes have been widely studied in relation to APAP pharmacokinetics in humans [20,23,26,93]

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They significantly improve the uptake efficiency of polyphenols by increasing their solubility, facilitating their absorption through endocytosis, and promoting the entrapment or surface adsorption of biomolecules (116)

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Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update)

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