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Description
1 H2RAs are generally well-tolerated, and toxicity is rare

[PubMed] [Google Scholar] 154.SuL G

This occurs in conditions such as pernicious anemia, an autoimmune condition that affects the production of intrinsic factor, which is necessary for the absorption of B12 in the small intestine

The mechanism involves the interaction of SAM with SAMTOR, an S-adenosylmethionine sensor that regulates the mTORC1 pathway (Gu et al., 2017)

J 24, 20.158
That factor turned out to be GHK-Cu