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A reduction in complex I was associated with a decrease in carnitine palmitoyltransferase 1 (cPT1) and cPT2 levels

1 Introduction Flavonoids, a diverse group of polyphenols naturally found in fruits, vegetables, coffee, and wine, transcend their well-known anti-inflammatory, antioxidant, and antitumor properties (Panche et al., 2016

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Fu LJ, Chen SB, Han LS, Guo Y, Zhao PJ, Zhu M, Li F, Huang MR

PMID 15466214

It is highly regulated at transcriptional, translational, and post-translational levels (29)

In a further study in patients with terminal cancer, the patients treated with carnitine (doses from 250 milligrams to 3000 milligrams/day) reported an improvement in the symptoms of fatigue as well as improved mood and sleep quality