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104 The CHIP/HOP balance is relevant for neurodegenerative diseases, as STUB1 is an important contributor to tau degradation

2024;20(46):e2403354

J., Campanaro, S., Valle, G

Overall, the research on the cytotoxicity and genotoxicity of glyphosate and Roundup is inconclusive and further investigation is needed to fully understand their effects

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Resistance to anti-EGFR monoclonal antibodies can develop from modulations to these pathways ( Loss of mismatch repair gene mutL homolog 1 (MLH1) has been shown to activate HER2/PI3K/Akt signaling to induce cetuximab resistance in colon cancer ( HER2 and heregulin upregulation have been shown to activate HER2 and ERK 1/2 signaling, leading to cetuximab resistance in various cancer cell lines