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Stem cell models enable rapid in vitro nanotoxicity screening across tissues

Necroinflammation The inflammatory responses that emerge when cells die via inflammatory cell death modalities such as necroptosis or pyroptosis which trigger the uncontrolled release of cellular contents (so-called danger signals) into surrounding tissues leading to activation of immune cells that drive inflammation

[DOI] [PubMed] [Google Scholar] 255.Pearson D.J., Suarez-Mendez V.J., Day J.P., Miller P.F

[DOI] [PMC free article] [PubMed] [Google Scholar] Querfurth, H

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Furthermore, the cancers, which rely on the mevalonate pathway for lipid synthesis, are vulnerable to lipid peroxidiation that highlights the prospect for selective ferroptosis [252]