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Dementia pugilistica and chronic symptoms Athletes exposed to repetitive concussions during contact sports are at an increased risk for the development of cognitive deficits

Informed Consent This manuscript did not involved human participants

Acamprosate is administered by mouth as delayed-release tablets, usually 666 mg taken three times a day, with or without food

results vary widely depending on individual metabolism, adherence, lifestyle, genetic factors

The protective effects of caspase-3 modulation extend beyond neurological tissue

They include flavanols (catechins), flavonols (kaempferol, quercetin), flavones (apigenin, luteolin), flavanones (hesperidin, naringenin), and anthocyanins [179]