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The aim of this study is to assess the effect of intra-articular injection of IGF-1 on the regeneration of chondrocytes in the femoral condyle and the anti-apoptotic effect of IGF-1 via downregulation of pro-inflammatory cytokine signaling in articular cartilage in OA
Methotrexate is used for short-term or long-term treatment
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Low levels of Vitamin B12 are rare in most healthy adults because the human liver stores it over time
MeCPs are a heterogeneous group that contain a methyl-CpG binding domain (MBD) [58]
Scale bar, 25 m in both figures and mags (n = 7 mice for V, n = 6 mice for R, P and P+R)
