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Concerning ABCB4 disease with at least one missense variant and a clinical phenotype with symptoms of hereditary cholestasis such as ICP, gallstone disease, LPAC ACC, DIC, UDCA therapy is recommended [91]
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10.1016/j.expneurol.2014.02.020 4 BabriS.MehrvashF.MohaddesG.HatamiH.MirzaieF
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In particular, the active participation of the nuclear envelope in apoptosis includes generation of nuclear protein-containing nuclear bubbles (GRUNB) in a Bax-dependent way and their rupture may amplify apoptotic signaling

Cell Biol Int 43:582592 Dai CC, Huang W, Yang J, Hussein WM, Wang J, Khalil ZG, Capon RJ, Toth I, Stephenson RJ (2021) Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines
