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Anaerobic respiration also produces lactate, which can induce the formation of a muscle cramp and muscle fatigue

Understanding how serum TMAO levels are regulated could uncover host TMAO mechanistic targets and identify modifiable and actionable therapeutic factors to lower circulating TMAO levels

Plasma TMAO concentrations were significantly higher in patients with ST-segment elevation myocardial infarction with plaque rupture than in patients exhibiting plaque erosion

2005, Haje & Naoom 2015, Tsounapi et al

Primary outcome measurements were analyzed at baseline and at weeks 3, 6, and 9
