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Another issue with clinical translation is patient genetic variation in the expression of NAD + synthesis genes, or lifestyle conditions changes, including exercise regimens, that would influence the effectiveness of interventions
10.1016/j.exger.2008.08.049 11 BeuraL
10.1016/j.jinorgbio.2012.06.011 175 Van LaarV
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The promoter of SLC1A5_Var contains hypoxia response elements, making its expression sensitive to hypoxia-inducible factor 2 (HIF2)
